Concepedia

Target Concentration Determination

Target Concentration Determination is a methodological framework within pharmacokinetic and pharmacodynamic modeling that identifies the optimal concentration range of a drug associated with therapeutic efficacy while minimizing adverse effects.

204

Publications

9.5K

Citations

1.1K

Authors

429

Institutions

Publications per year

2017–2026

63

Parents

Publications

204

Mathematics of quantitative kinetic PCR and the application of standard curves

Robert G. Rutledge · Nucleic Acids Research · 2003 · 537 citations · Full text

, , +13

Lamotrigine in pregnancy

Page B. Pennell, Lilei Peng, D. Jeffrey Newport et al. · Neurology · 2007 · 287 citations · Full text

, , +17

Comparison of Plasma Compartment versus  Two Methods for Effect Compartment–controlled Target-controlled Infusion for Propofol

Michel Struys, Tom De Smet, Birgit Depoorter et al. · Anesthesiology · 2000 · 267 citations

, , +13

Protein Binding of β-Lactam Antibiotics in Critically Ill Patients: Can We Successfully Predict Unbound Concentrations?

Gloria Wong, Scott Briscoe, Syamhanin Adnan et al. · Antimicrobial Agents and Chemotherapy · 2013 · 221 citations · Full text

, , +17

Evaluation of the predictive performance of a ‘Diprifusor’ TCI system

C. F. Swinhoe, J.E. Peacock, J. B. Glen et al. · Anaesthesia · 1998 · 190 citations

, , +13

1–5 of 204

Authors

1.1K

  1. GN
    G. N. C. Kenny

    Glasgow Royal Infirmary, United Kingdom

    5 publications · 468 citations

    5

    h-index

  2. YT
    Yoshiko Takahashi

    Hyogo Medical University, Japan

    3 publications · 160 citations

    3

    h-index

  3. MU
    Motoi Uchino

    Hyogo Medical University, Japan

    3 publications · 160 citations

    3

    h-index

  4. TK
    Takeshi Kimura

    Kyoto University, Japan

    3 publications · 160 citations

    3

    h-index

  5. BM
    Brett McWhinney

    The University of Queensland, Australia

    3 publications · 455 citations

    3

    h-index

1–5 of 1.1K

Institutions

429

  1. Inserm

    Paris, France

    6 h-index

    29 publications

    2.8K citations

  2. Université Paris Cité

    Paris, France

    5 h-index

    21 publications

    1.6K citations

  3. Glasgow Royal Infirmary

    Glasgow, United Kingdom

    5 h-index

    9 publications

    899 citations

  4. Uppsala University

    Uppsala, Sweden

    4 h-index

    8 publications

    532 citations

  5. Assistance Publique – Hôpitaux de Paris

    Paris, France

    4 h-index

    24 publications

    1.4K citations

  6. Radboud University Nijmegen

    Nijmegen, The Netherlands

    4 h-index

    3 publications

    112 citations

  7. Leiden University Medical Center

    Leiden, The Netherlands

    3 h-index

    9 publications

    361 citations

  8. Hôpital Bichat-Claude-Bernard

    Paris, France

    3 h-index

    14 publications

    1K citations

1–8 of 429

Venues

  1. Analytical Chemistry

    13 publications · 682 citations

    13

    h-index

  2. Anaesthesia

    13 publications · 874 citations

    12

    h-index

  3. Therapeutic Drug Monitoring

    11 publications · 369 citations

    11

    h-index

  4. Anesthesiology

    6 publications · 516 citations

    6

    h-index

  5. Antimicrobial Agents and Chemotherapy

    AAC · 4 publications · 362 citations

    5

    h-index

1–5