Chemical Communications · 2005 · 106 citations · 37 references
PharmacyBiochemistryChemistryCombinatorial ChemistryChemical Library DesignCombinatorial SynthesisDisulfide Bond FormationDiversity-oriented SynthesisDynamic Combinatorial ChemistryDisulfide Bond RearrangementDisulfide ContributionsDisulfide Exchange ChemistryDisulfide LinkersDiversity-generating ReactionsDynamic Combinatorial LibrariesThioester Chemistry
Dynamic combinatorial libraries have been prepared which feature two simultaneous covalent exchange reactions in aqueous solution at neutral pH. This allows for diversity, not only of the subunits that are linked, but also of the linkage itself.
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