Cell Death and Differentiation · 2003 · 143 citations · 47 references
MedicineMolecular BiologyOncologyCancer GeneticsChemotherapyMolecular OncologyApoptosis ResistanceChemotherapy In Hematologic MalignanciesChemotherapy ResistanceCytotoxic ChemotherapyDna Damage-induced ApoptosisTherapeutic ResistanceAnticancer Drug ResistanceDrug Resistance MutationsGenetic Alterations In ResistanceMolecular Drug ResistanceP53 MutationTherapeutic Resistance MechanismsTp53 Mutations
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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
Scott W. Lowe, H. Earl Ruley, Tyler Jacks et al. · Cell · 1993 · 2.9K citations
PUMA, a Novel Proapoptotic Gene, Is Induced by p53
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Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
Eri Oda, Rieko Ohki, Hideki Murasawa et al. · Science · 2000 · 2.1K citations
A Senescence Program Controlled by p53 and p16INK4a Contributes to the Outcome of Cancer Therapy
Clemens A. Schmitt, Jordan S. Fridman, Meng Yang et al. · Cell · 2002 · 1K citations · Full text
Medicine, Cancer Biology, Oncology +16