Concepedia

The p66shc adaptor protein controls oxidative stress response and life span in mammals

Enrica Migliaccio, Marco Giorgio, Simonetta Mele, Giuliana Pelicci, Pier Paolo Pandolfi, Luisa Lanfrancone, Pier Giuseppe Pelicci

Nature · 1999 · 1.7K citations · 26 references

DOI

Concepts

References

26

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Pumin Zhang, J. Wade Harper, Stephen J. Elledge et al. · Cell · 1995 · 2.1K citations · Full text

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Extension of Life-Span by Overexpression of Superoxide Dismutase and Catalase in <i>Drosophila melanogaster</i>

William C. Orr, Rajindar S. Sohal · Science · 1994 · 1.5K citations

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

Giuliana Pelicci, Luisa Lanfrancone, F Grignani et al. · Cell · 1992 · 1.3K citations

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p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.

Kay F. Macleod, Norelle L. Sherry, Gregory J. Hannon et al. · Genes & Development · 1995 · 1.1K citations · Full text

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The Retardation of Aging in Mice by Dietary Restriction: Longevity, Cancer, Immunity and Lifetime Energy Intake

Richard Weindruch, Roy L. Walford, Suzanne Fligiel et al. · Journal of Nutrition · 1986 · 1K citations

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