Omega-3 Fatty Acids and Other FFA4 Agonists Inhibit Growth Factor Signaling in Human Prostate Cancer Cells

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

Da Young Oh, Saswata Talukdar, Eun Ju Bae et al. · Cell · 2010 · 2.4K citations · Full text

Medicine, Endocrinology, Pharmacology +12

Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation

Yiqing Yan, Wei Jiang, Thibaud Spinetti et al. · Immunity · 2013 · 756 citations · Full text

Life Sciences, Immunology, Nutritional Sciences +16

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

Celia P. Briscoe, Andrew J. Peat, Stephen C. McKeown et al. · British Journal of Pharmacology · 2006 · 400 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17

A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells

Meryem Bektas, Shawn G. Payne, Hong Liu et al. · The Journal of Cell Biology · 2005 · 220 citations · Full text

Life Sciences, Biochemistry, Oncology +17

The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

Brian D. Hudson, Bharat Shimpukade, Amanda E. Mackenzie et al. · Molecular Pharmacology · 2013 · 202 citations

Medicine, Biochemistry, Pharmacology +15