Brian D. Hudson

Strategic Pooling of Compounds for High-Throughput Screening

Mike Hann, Brian D. Hudson, Xiao Qing Lewell et al. · Journal of Chemical Information and Computer Sciences · 1999 · 230 citations

Pharmaceutical Research, Hit Identification, Effective Drugs +20

The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

Brian D. Hudson, Bharat Shimpukade, Amanda E. Mackenzie et al. · Molecular Pharmacology · 2013 · 197 citations · Full text

Discovery of a Potent and Selective GPR120 Agonist

Bharat Shimpukade, Brian D. Hudson, Christine Kiel Hovgaard et al. · Journal of Medicinal Chemistry · 2012 · 160 citations · Full text

Metabolic Syndrome, Selective Gpr120 Agonist, Biochemistry +13

Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3

Brian D. Hudson, Irina G. Tikhonova, Sunil K. Pandey et al. · Journal of Biological Chemistry · 2012 · 138 citations · Full text

Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor

Brian D. Hudson, Maria E. Due‐Hansen, Elisabeth Christiansen et al. · Journal of Biological Chemistry · 2013 · 122 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Only Selective Ligands +15