Nature · 2013 · 630 citations · 19 references
Life SciencesCell BiologyMolecular BiologyCellular MetabolismMitochondrial BiologyOncogenesCellular RespirationCellular SenescenceMitochondrial BioenergeticsMitochondrial MetabolismMitochondrial PhysiologyOncogene-induced SenescenceCell SenescenceMetabolic Reprogramming In SenescenceOncogene-induced Senescence PathwaysPyruvate Dehydrogenase DeficiencyPyruvate MetabolismPyruvate OxidationSenescence
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Mutations of the BRAF gene in human cancer
Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text
Medicine, Cell Biology, Oncology +10
BRAFE600-associated senescence-like cell cycle arrest of human naevi
Chrysiis Michaloglou, Liesbeth C.W. Vredeveld, Marı́a S. Soengas et al. · Nature · 2005 · 2.1K citations · Full text
Life Sciences, Biology, Cell Biology +12