Synthesis of Cell‐Laden Alginate Hollow Fibers Using Microfluidic Chips and Microvascularized Tissue‐Engineering Applications

Abstract

Alginate-only, cell-laden, and protein-immobilized hollow fibers are produced (see image). Cells remain alive within the hollow fibers due to the nontoxic fabrication process. Vascular tissue can be emulated by embedding endothelial cells into the alginate hollow fibers and then embedding these cell-laden fibers into smooth-muscle-cell-laden AGF hydrogels. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.