Concepedia

8-Oxo-7,8-dihydroguanine: Links to gene expression, aging, and defense against oxidative stress

Zsolt Radák, István Boldogh

Free Radical Biology and Medicine · 2010 · 156 citations · 150 references

DOI

Concepts

References

150

Aging: A Theory Based on Free Radical and Radiation Chemistry

Denham Harman · Journal of Gerontology · 1956 · 8.5K citations

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein et al. · Nature · 2000 · 3.5K citations

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The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

Alberto Boveris, Britton Chance · Biochemical Journal · 1973 · 2.6K citations · Full text

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The Biologic Clock: The Mitochondria?

Denham Harman · Journal of the American Geriatrics Society · 1972 · 2K citations

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Gene regulation and DNA damage in the ageing human brain

Tao Lu, Ying Pan, Shyan‐Yuan Kao et al. · Nature · 2004 · 1.9K citations

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