Concepedia

Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass Spectrometry

Boram Lee, Hyeon‐Kyeong Ji, Tae‐Ho Lee, Kwang‐Hyeon Liu

Drug Metabolism and Disposition · 2015 · 21 citations · 37 references

DOI

Concepts

References

37

VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES

Robert L. Walsky, R. Scott Obach · Drug Metabolism and Disposition · 2004 · 504 citations

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In Vitro Glucuronidation Using Human Liver Microsomes and The Pore-Forming Peptide Alamethicin

Michael B. Fisher, Kristina Campanale, Bradley L. Ackermann et al. · Drug Metabolism and Disposition · 2000 · 342 citations

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HUMAN UDP-GLUCURONOSYLTRANSFERASES: ISOFORM SELECTIVITY AND KINETICS OF 4-METHYLUMBELLIFERONE AND 1-NAPHTHOL GLUCURONIDATION, EFFECTS OF ORGANIC SOLVENTS, AND INHIBITION BY DICLOFENAC AND PROBENECID

Verawan Uchaipichat, Peter I. Mackenzie, Xiao-Hui Guo et al. · Drug Metabolism and Disposition · 2004 · 334 citations

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Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development.

Paweł Baranczewski, Andrzej Stańczak, Kathrin Sundberg et al. · PubMed · 2007 · 290 citations

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IN VITRO INHIBITION OF UDP GLUCURONOSYLTRANSFERASES BY ATAZANAVIR AND OTHER HIV PROTEASE INHIBITORS AND THE RELATIONSHIP OF THIS PROPERTY TO IN VIVO BILIRUBIN GLUCURONIDATION

Donglu Zhang, Theodore J. Chando, Donald W. Everett et al. · Drug Metabolism and Disposition · 2005 · 286 citations

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