TAK1 downregulation reduces IL-1β induced expression of MMP13, MMP1 and TNF-alpha

Biologic basis for interleukin-1 in disease

CA Dinarello · Blood · 1996 · 4.3K citations · Full text

Activators and target genes of Rel/NF-κB transcription factors

Heike L. Pahl · Oncogene · 1999 · 3.7K citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +9

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

Signal Transduction, Signaling Pathway, Cell Regulation +6

Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-β Signal Transduction

Kyoko Shirakabe, Hiroshi Shibuyà, Kenji Irie et al. · Science · 1995 · 1.3K citations

Cellular Physiology, Signaling Pathway, Cell Regulation +18

The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway

Jun Ninomiya‐Tsuji, Kazuya Kishimoto, Atsushi Hiyama et al. · Nature · 1999 · 1.2K citations

Inflammation, Cytokine, Il-1 Signalling Pathway +13