Concepedia

mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc

Kenta Masui, Kazuhiro Tanaka, David Akhavan, Ivan Babić, Beatrice Gini, Tomoo Matsutani, Akio Iwanami, Feng Liu, Genaro R. Villa, Yuchao Gu,

Cell Metabolism · 2013 · 400 citations · 32 references

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32

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature · 2008 · 7.8K citations · Full text

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Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase

Anne Brunet, Lora B. Sweeney, James Fitzhugh Sturgill et al. · Science · 2004 · 3.2K citations

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TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis

Karim Bensaad, Atsushi Tsuruta, Mary Selak et al. · Cell · 2006 · 2K citations · Full text

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Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

David A. Guertin, Deanna M. Stevens, Carson C. Thoreen et al. · Developmental Cell · 2006 · 1.4K citations · Full text

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