Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development

Yaoqin Gong, Roger B. Slee, N Fukai et al. · Cell · 2001 · 2.2K citations · Full text

Bone Accrual, Sclerostin, Signal Transduction +8

Wnt/β-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis

Timothy F. Day, Xizhi Guo, Lisa Garrett‐Beal et al. · Developmental Cell · 2005 · 1.6K citations · Full text

Developmental Biology, Vertebrate Skeletogenesis, Bone Morphogenic Protein +7

High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5

Lynn M. Boyden, Junhao Mao, Joseph L. Belsky et al. · New England Journal of Medicine · 2002 · 1.6K citations · Full text

The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma

Erming Tian, Fenghuang Zhan, Ronald C. Walker et al. · New England Journal of Medicine · 2003 · 1.5K citations · Full text

A Mutation in the LDL Receptor–Related Protein 5 Gene Results in the Autosomal Dominant High–Bone-Mass Trait

Randall D. Little, Colleen Folz, Susan P. Manning et al. · The American Journal of Human Genetics · 2002 · 1.3K citations · Full text

Bone Disease, Genetics, Genetic Epidemiology +4