Frank Asuncion

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

Xiaodong Li, Michael S. Ominsky, Qing‐Tian Niu et al. · Journal of Bone and Mineral Research · 2008 · 938 citations · Full text

Medicine, Genetics, Molecular Genetics +17

Denosumab, a Fully Human Monoclonal Antibody to RANKL, Inhibits Bone Resorption and Increases BMD in Knock-In Mice That Express Chimeric (Murine/Human) RANKL

Paul J. Kostenuik, Hung Q. Nguyen, James McCabe et al. · Journal of Bone and Mineral Research · 2008 · 436 citations

Medicine, Immunology, Molecular Medicine +17

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

Ji Li, Ildiko Sarosi, Russell C. Cattley et al. · Bone · 2006 · 434 citations

Medicine, Orthopedic Surgery, Bone Metabolism +11

Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones

Michael S. Ominsky, Chaoyang Li, Xiaodong Li et al. · Journal of Bone and Mineral Research · 2010 · 265 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

Mónica Florio, Kannan Gunasekaran, Marina Stolina et al. · Nature Communications · 2016 · 253 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +17