Initiation of Signal Transduction through the T Cell Receptor Requires the Multivalent Engagement of Peptide/MHC Ligands

Phenotypic Analysis of Antigen-Specific T Lymphocytes

John D. Altman, Paul Moss, Philip Goulder et al. · Science · 1996 · 3.6K citations

Life Sciences, Cell Biology, Immunology +17

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

Jerry H. Brown, Theodore S. Jardetzky, Joan C. Gorga et al. · Nature · 1993 · 2.4K citations

Life Sciences, Immunology, Molecular Biology +12

Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation

David W. Banner, A. D’Arcy, Wolfgang Janes et al. · Cell · 1993 · 1.1K citations

Life Sciences, Biochemistry, Immunology +17

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

David B. Straus · Cell · 1992 · 1K citations

Life Sciences, Immunology, Molecular Biology +16

Kinetic proofreading in T-cell receptor signal transduction.

Timothy W. McKeithan · Proceedings of the National Academy of Sciences · 1995 · 985 citations

Life Sciences, Biochemistry, Immunology +17