Concepedia

Increased plasma S-adenosyl-homocysteine levels induce the proliferation and migration of VSMCs through an oxidative stress-ERK1/2 pathway in apoE−/− mice

Xiaoqin Luo, Yunjun Xiao, Feng-Lin Song, Yan Yang, Min Xia, Wenhua Ling

Cardiovascular Research · 2012 · 63 citations · 36 references

DOIFull text

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Abstract

Our results suggest that elevated SAH induces VSMC proliferation and migration through an oxidative stress-dependent activation of the ERK1/2 pathway to promote atherogenesis.

References

36

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