Concepedia

Human CYP2C8 Is Transcriptionally Regulated by the Nuclear Receptors Constitutive Androstane Receptor, Pregnane X Receptor, Glucocorticoid Receptor, and Hepatic Nuclear Factor 4α

Stephen Ferguson, Yuping Chen, Edward L. LeCluyse, Masahiko Negishi, Joyce A. Goldstein

Molecular Pharmacology · 2005 · 196 citations · 31 references

DOI

Concepts

References

31

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Proceedings of the National Academy of Sciences · 2002 · 1.8K citations · Full text

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Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.

Tim Cole, Julie A. Blendy, A. Paula Monaghan et al. · Genes & Development · 1995 · 947 citations · Full text

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St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

Linda B. Moore, Bryan Goodwin, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 2000 · 938 citations

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Cytochrome P450 2C is an EDHF synthase in coronary arteries

Beate Fißlthaler, Rüdiger Popp, Ladislau Kiss et al. · Nature · 1999 · 910 citations

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Nuclear Receptor Response Elements Mediate Induction of Intestinal MDR1 by Rifampin

Anke Geick, Michel Eichelbaum, Oliver Burk · Journal of Biological Chemistry · 2001 · 841 citations · Full text

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