Concepedia

Publication | Closed Access

Plasma Pharmacokinetics, Oral Bioavailability, and Interspecies Scaling of the DNA Methyltransferase Inhibitor, Zebularine

DOI

93

Citations

11

References

2005

Year

Julianne L. Holleran, Robert A. Parise, Erin Joseph, Julie L. Eiseman, Joseph M. Covey, Elizabeth R. Glaze, Alexander V. Lyubimov, Ya-Fei Chen, David Z. D’Argenio, Merrill J. Egorin
Clinical Cancer Research

Abstract

Zebularine has limited oral bioavailability. Interspecies scaling projects a CL(tb) of 296 mL/min in humans.

References

YearCitations

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