High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 6.9K citations · Full text

Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target

Angela N Kuntz, Elisabeth Davioud–Charvet, Ahmed A. Sayed et al. · PLoS Medicine · 2007 · 359 citations · Full text

Cultivation of Schistosoma mansoni In vitro. I. Establishment of Cultures from Cercariae and Development until Pairing

Paul F. Basch · Journal of Parasitology · 1981 · 326 citations · Full text

Schistosoma Mansoni, Parasitic Disease, Mass Cultivation +9

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

Ahmed A. Sayed, Anton Simeonov, Craig J. Thomas et al. · Nature Medicine · 2008 · 269 citations · Full text

New Drug, Medicinal Chemistry, Antiparasitic Agent +11

The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase

Heather M. Alger, David L. Williams · Molecular and Biochemical Parasitology · 2002 · 174 citations

Schistosoma Mansoni, Bioorganic Chemistry, Aldo-keto Reductase +12