Concepedia

An Assessment of the Mechanistic Differences Between Two Integrin α4β1 Inhibitors, the Monoclonal Antibody TA-2 and the Small Molecule BIO5192, in Rat Experimental Autoimmune Encephalomyelitis

Diane R. Leone, Keith Giza, Alan Gill, Brian Dolinski, William J. Yang, Stuart J. Perper, Daniel M. Scott, W.-C. Lee, Mark Cornebise, Kathleen Wortham,

Journal of Pharmacology and Experimental Therapeutics · 2003 · 60 citations · 36 references

DOI

Concepts

References

36

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

Ted Yednock, Catherine Cannon, Lawrence C. Fritz et al. · Nature · 1992 · 1.7K citations

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Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

Laurelee Osborn, Catherine Hession, Richard Tizard et al. · Cell · 1989 · 1.7K citations

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A Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis

David H. Miller, Omar Khan, William Sheremata et al. · New England Journal of Medicine · 2003 · 1.2K citations · Full text

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Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin.

Elizabeth A. Wayner, Angeles Garcı́a-Pardo, Martin J. Humphries et al. · The Journal of Cell Biology · 1989 · 794 citations · Full text

, , +16

Circulating integrins: alpha 5 beta 1, alpha 6 beta 4 and Mac‐1, but not alpha 3 beta 1, alpha 4 beta 1 or LFA‐1.

Mark S. Bretscher · The EMBO Journal · 1992 · 217 citations · Full text

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