FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure, and Weight Loss

FGF-21 as a novel metabolic regulator

Alexei Kharitonenkov, Tatiyana L. Shiyanova, Anja Köester et al. · Journal of Clinical Investigation · 2005 · 2.1K citations · Full text

Obesity, Metabolic Syndrome, Novel Metabolic Regulator +14

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

Ffolliott M. Fisher, Sandra Kleiner, Nicholas Douris et al. · Genes & Development · 2012 · 1.4K citations · Full text

Human Growth, Metabolic Remodeling, Cellular Physiology +20

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

Jing Xu, David J. Lloyd, Clarence Hale et al. · Diabetes · 2008 · 1.1K citations · Full text

Fibroblast Growth Factor 21 Corrects Obesity in Mice

Tamer Coşkun, Holly A. Bina, M. Schneider et al. · Endocrinology · 2008 · 1K citations

Nutrition, Metabolic Disorder, Corrects Obesity +23

The Effects of LY2405319, an FGF21 Analog, in Obese Human Subjects with Type 2 Diabetes

Gregory Gaich, Jenny Y. Chien, Haoda Fu et al. · Cell Metabolism · 2013 · 867 citations · Full text

Obesity, Metabolic Syndrome, Health Sciences +10