Inhibition of Biliary Excretion of Methotrexate by Probenecid in Rats: Quantitative Prediction of Interaction from in Vitro Data

A pharmacokinetic analysis program (multi) for microcomputer.

Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics · 1981 · 2.5K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

BindingDB Entry 50042069: Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats.

PubMed · 2013 · 172 citations · Full text

Pharmacy, Biochemistry, Pharmacology +17

Prolongation and enhancement of serum methotrexate concentrations by probenecid.

G. Wynne Aherne, E. M. Piall, V. Marks et al. · BMJ · 1978 · 113 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +13

Interactions in the renal and biliary elimination of digoxin: Stereoselective difference between quinine and quinidine

Ann Hedman, Bo Angelin, Annie Arvidsson et al. · Clinical Pharmacology & Therapeutics · 1990 · 74 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Digoxin-verapamil interaction: Reduction of biliary but not renal digoxin clearance in humans

Ann Hedman, Bo Angelin, Annie Arvidsson et al. · Clinical Pharmacology & Therapeutics · 1991 · 70 citations

Pharmacy, Pharmacokinetics, Pharmacology +11