Concepedia

Platelet Inhibition by Insulin Is Absent in Type 2 Diabetes Mellitus

Irlando Andrade Ferreira, Astrid I.M. Mocking, Marion A.H. Feijge, Gertie Gorter, Timon W. van Haeften, Johan W. M. Heemskerk, Jan‐Willem N. Akkerman

Arteriosclerosis Thrombosis and Vascular Biology · 2005 · 207 citations · 46 references

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Abstract

The loss of responsiveness to insulin together with increased signaling through P2y12 might explain the hyperactivity of platelets in patients with DM2.

References

46

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

Diabetes Care · 2002 · 10.4K citations

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A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)

The Lancet · 1996 · 6.5K citations

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Insulin signalling and the regulation of glucose and lipid metabolism

Alan R. Saltiel, C. Ronald Kahn · Nature · 2001 · 5.2K citations · Full text

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COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS

Robert Altman, L Carreras, Rubén Sierra Díaz et al. · Oxford University Research Archive (ORA) (University of Oxford) · 1994 · 3.3K citations

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