EXP3179 Inhibits Collagen-Dependent Platelet Activation via Glycoprotein Receptor-VI Independent of AT <sub>1</sub> -Receptor Antagonism - Concepedia

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EXP3179 Inhibits Collagen-Dependent Platelet Activation via Glycoprotein Receptor-VI Independent of AT <sub>1</sub> -Receptor Antagonism

50

Citations

24

References

2007

Year

Christina Grothusen, Sumaira Umbreen, Ildiko Konrad, Konstantinos Stellos, Christian Schulz, Boris Schmidt, Elisabeth Kremmer, Omke E. Teebken, Maren Luchtefeld, Bernhard Schieffer,

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

EXP3179 acts as a specific inhibitor of the platelet collagen receptor GPVI independent of AT1-receptor antagonism. Further investigations may clarify its individual potential as a novel pharmacological approach to specifically inhibit atherothrombotic events by GPVI-receptor blockade.

References

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