Concepedia

Endothelial Microparticle Levels Are Similar in Acute Ischemic Stroke and Stroke Mimics Due to Activation and Not Apoptosis/Necrosis

Justin Williams, Edward C. Jauch, Christopher J. Lindsell, Begoña Campos

Academic Emergency Medicine · 2007 · 47 citations · 16 references

DOIFull text

Open access

Abstract

EMP levels were similar in patients with AIS and stroke mimic patients. The PECAM-1/E-selectin ratio demonstrated that EMPs were generated via activation and not apoptosis/necrosis. This suggests that EMPs may not be a good marker for AIS, given the inability to discriminate between stroke mimics and AIS.

References

16

Elevated Levels of Shed Membrane Microparticles With Procoagulant Potential in the Peripheral Circulating Blood of Patients With Acute Coronary Syndromes

Ziad Mallat, Hakim Benamer, Bénédicte Hugel et al. · Circulation · 2000 · 870 citations

Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis

Joaquín J. Jiménez, Wenche Jy, Lucía Mercedes Mauro et al. · Thrombosis Research · 2003 · 506 citations

, , +14

Circulating Microparticles From Patients With Myocardial Infarction Cause Endothelial Dysfunction

Chantal M. Boulanger, Alexandra Scoazec, Talin Ebrahimian et al. · Circulation · 2001 · 495 citations · Full text

Effects of Severe Hypertension on Endothelial and Platelet Microparticles

Richard A. Preston, Wenche Jy, Joaquín J. Jiménez et al. · Hypertension · 2003 · 492 citations

, , +15

Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus.

Livia Casciola‐Rosen, Antony Rosen, Michelle Petri et al. · Proceedings of the National Academy of Sciences · 1996 · 485 citations · Full text

, , +20