Bariatric Surgery Cannot Prevent Tryptophan Depletion Due to Chronic Immune Activation in Morbidly Obese Patients

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Haiyan Xu, Glenn T. Barnes, Qing Yang et al. · Journal of Clinical Investigation · 2003 · 5.8K citations · Full text

Metabolic Disorder, Immunology, Insulin Signaling +18

Years of Life Lost Due to Obesity

Kevin R. Fontaine, David T. Redden, Chenxi Wang et al. · JAMA · 2003 · 2.5K citations

Elevated C-Reactive Protein Levels in Overweight and Obese Adults

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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Catherine Uyttenhove, Luc Pilotte, Ivan Théate et al. · Nature Medicine · 2003 · 2.3K citations

Inflammation, Cancer Immunosurveillance, Biochemistry +8

C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men

Wolfgang Köenig, M. Sund, Margit Fröhlich et al. · Circulation · 1999 · 1.9K citations · Full text