Effects of<i>CYP2C9</i>and<i>VKORC1</i>on INR Variations and dose Requirements During Initial Phase of Anticoagulant Therapy

Abstract

The determination of VKORC1*3 and VKORC1*4 haplotypes may be an important addition to CYP2C9 and VKORC1*2 genotyping to identify patients at risk of being outside the target range during initial anticoagulation with acenocoumarol.