Concepedia

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles

Lorenzo A. Orci, Mariella Ravazzola, M. Storch, Richard G.W. Anderson, J D Vassalli, Alain Perrelet

Cell · 1987 · 337 citations · 10 references

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10

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

Paul E. Lacy, Mery Kostianovsky · Diabetes · 1967 · 2.8K citations

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Ultrastructural localization of intracellular antigens by the use of protein A-gold complex.

Jürgen Roth, M Bendayan, Lelio Orci · Journal of Histochemistry & Cytochemistry · 1978 · 986 citations · Full text

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Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles.

Lelio Orci, Mariella Ravazzola, M Amherdt et al. · The Journal of Cell Biology · 1986 · 335 citations · Full text

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Direct identification of prohormone conversion site in insulin-secreting cells

Lelio Orci, Mariella Ravazzola, M Amherdt et al. · Cell · 1985 · 304 citations · Full text

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Visualization of acidic organelles in intact cells by electron microscopy.

R G Anderson, John R. Falck, J L Goldstein et al. · Proceedings of the National Academy of Sciences · 1984 · 250 citations · Full text

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