Targeting tuberculosis through a small focused library of 1,2,3-triazoles

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.4K citations

Terminal Alkynes, Chemical Engineering, Novel Organocatalysts +12

Genes required for mycobacterial growth defined by high density mutagenesis

Christopher M. Sassetti, Dana Boyd, Eric J. Rubin · Molecular Microbiology · 2003 · 2.6K citations · Full text

A Microwave-Assisted Click Chemistry Synthesis of 1,4-Disubstituted 1,2,3-Triazoles via a Copper(I)-Catalyzed Three-Component Reaction

Prasad Appukkuttan, Wim Dehaen, Valery V. Fokin et al. · Organic Letters · 2004 · 557 citations

Cross-coupling Reaction, Engineering, Organic Azides +12

Inactivation of the <i>inhA</i> -Encoded Fatty Acid Synthase II (FASII) Enoyl-Acyl Carrier Protein Reductase Induces Accumulation of the FASI End Products and Cell Lysis of <i>Mycobacterium smegmatis</i>

Catherine Vilchèze, Héctor R. Morbidoni, Torin R. Weisbrod et al. · Journal of Bacteriology · 2000 · 278 citations

High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains of <i>Mycobacterium tuberculosis</i>

Todd J. Sullivan, J.J. Truglio, Melissa E. Boyne et al. · ACS Chemical Biology · 2006 · 232 citations · Full text

Mtb Results, Tuberculosis Prevention, Antimicrobial Chemotherapy +17