Uridine Diphosphate-N-acetyl-d-galactosamine:d-Galactose α-3-N-Acetyl-d-galactosaminyltransferase, a Product of the Gene That Determines Blood Type A in Man

Abstract

Abstract An N-acetyl-d-galactosaminyltransferase which occurs in human milk from donors of blood type A or AB but not in milk from donors of blood type B or O has been purified 55-fold, and its properties have been studied. The enzyme catalyzes the following reaction which results in the formation of structural determinants of blood type A. [see PDF for equation]