Fibrinogen Induces Biofilm Formation by <i>Streptococcus suis</i> and Enhances Its Antibiotic Resistance

Abstract

In this study, we showed that supplementing the culture medium with fibrinogen induced biofilm formation by Streptococcus suis in a dose-dependent manner. Biofilm-grown S. suis cells were much more resistant to penicillin G than planktonic cells. S. suis bound fibrinogen to its surface, a property that likely contributes to biofilm formation.