Concepedia

Fibrinogen Binding

Fibrinogen Binding is a molecular interaction process in which fibrinogen, a plasma glycoprotein, selectively attaches to activated integrin receptors on platelet membranes, thereby mediating platelet aggregation during hemostasis and thrombosis.

3.5K

Publications

204.7K

Citations

11.5K

Authors

2.2K

Institutions

Publications per year

2017–2026

240

Parents

Publications

3.5K

Fibrinogen and risk of cardiovascular disease. The Framingham Study

William B. Kannel · JAMA · 1987 · 1.2K citations

, , +14

Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor

Brian Savage, Enrique Saldı́var, Zaverio M. Ruggeri · Cell · 1996 · 1.2K citations · Full text

, , +14

Thrombolysis in myocardial infarction (TIMI) trial—Phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase

Anupama Rao, Craig M. Pratt, Andrew Berke et al. · Journal of the American College of Cardiology · 1988 · 988 citations

, , +17

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.

Sanford J. Shattil, James A. Hoxie, Michael Cunningham et al. · Journal of Biological Chemistry · 1985 · 954 citations · Full text

, , +17

Effects of Platelet Glycoprotein IIb/IIIa Blockade With Tirofiban on Adverse Cardiac Events in Patients With Unstable Angina or Acute Myocardial Infarction Undergoing Coronary Angioplasty

The RESTORE Investigators · Circulation · 1997 · 948 citations

, , +17

1–5 of 3.5K

Authors

11.5K

  1. EF
    Edward F. Plow

    Cleveland Clinic, United States

    35 publications · 4.7K citations

    28

    h-index

  2. ST
    Susan T. Lord

    University of North Carolina at Chapel Hill, United States

    36 publications · 1.5K citations

    24

    h-index

  3. BB
    Birger Blombäck

    Karolinska Institutet, Sweden

    32 publications · 2.5K citations

    24

    h-index

  4. SJ
    Sanford J. Shattil

    Scripps Research Institute, United States

    23 publications · 4.3K citations

    23

    h-index

  5. MH
    Mark H. Ginsberg

    University of California San Diego, United States

    24 publications · 4.5K citations

    23

    h-index

1–5 of 11.5K

Institutions

2.2K

  1. Scripps Research Institute

    San Diego, United States

    43 h-index

    178 publications

    32.3K citations

  2. University of Pennsylvania

    Philadelphia, United States

    41 h-index

    238 publications

    29.2K citations

  3. Inserm

    Paris, France

    39 h-index

    343 publications

    22.1K citations

  4. University of Washington

    Seattle, United States

    39 h-index

    176 publications

    18.1K citations

  5. Karolinska Institutet

    Stockholm, Sweden

    36 h-index

    180 publications

    14K citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    36 h-index

    246 publications

    13.5K citations

  7. Temple University

    Philadelphia, United States

    35 h-index

    203 publications

    13.7K citations

  8. McMaster University

    Hamilton, Canada

    34 h-index

    199 publications

    13.3K citations

1–8 of 2.2K

Venues

  1. Journal of Biological Chemistry

    JBC · 235 publications · 22.2K citations

    86

    h-index

  2. Blood

    231 publications · 15.8K citations

    68

    h-index

  3. Journal of Clinical Investigation

    JCI · 70 publications · 11.7K citations

    58

    h-index

  4. Thrombosis and Haemostasis

    200 publications · 8.2K citations

    51

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 63 publications · 7.9K citations

    45

    h-index

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