Betaine supplement enhances skeletal muscle differentiation in murine myoblasts via IGF-1 signaling activation

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Sue C. Bodine, Trevor N. Stitt, Michael Gonzalez et al. · Nature Cell Biology · 2001 · 2.7K citations

Skeletal Muscle Hypertrophy, Molecular Physiology, Muscle Injury +10

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways

Christian Rommel, Sue C. Bodine, Brian Clarke et al. · Nature Cell Biology · 2001 · 1.6K citations

Molecular Physiology, Signal Transduction, Signaling Pathway +8

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

Orna Halevy, Bennett G. Novitch, Douglas B. Spicer et al. · Science · 1995 · 1.1K citations

Transcriptional Regulation, Skeletal Muscle Differentiation, Muscle Function +15

Single-Cell Analysis of Regulatory Gene Expression in Quiescent and Activated Mouse Skeletal Muscle Satellite Cells

DDW Cornelison, B Wold · Developmental Biology · 1997 · 932 citations

Signal Transduction, Developmental Biology, Skeletal Muscle +9

Myogenic Vector Expression of Insulin-like Growth Factor I Stimulates Muscle Cell Differentiation and Myofiber Hypertrophy in Transgenic Mice

Michael Coleman, Francesco J. DeMayo, Kuo Chang Yin et al. · Journal of Biological Chemistry · 1995 · 635 citations · Full text

Myogenic Expression Vector, Transgene Expression, Cytoskeleton +18