Concepedia

A General Solution to the Modular Synthesis of Polyketide Building Blocks by Kanemasa Hydroxy-Directed Nitrile Oxide Cycloadditions This work was supported by the ETH-Zürich, Hoffmann-LaRoche, Merck, and Novartis. J.W.B. thanks the National Science Foundation (USA) for a predoctoral fellowship. We are grateful to Boehringer-Ingelheim for a generous gift of (R)-3-buten-2-ol.

Jeffrey W. Bode, Nina Fraefel, Dieter Muri, Erick M. Carreira

PubMed · 2001 · 107 citations · 28 references

DOI

Concepts

Abstract

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References

28

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First Successful Metal Coordination Control in 1,3-Dipolar Cycloadditions. High-Rate Acceleration and Regio- and Stereocontrol of Nitrile Oxide Cycloadditions to the Magnesium Alkoxides of Allylic and Homoallylic Alcohols

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, , +13