Concepedia

Nitrile Oxide Cycloaddition

Nitrile Oxide Cycloaddition is a bioorthogonal reaction that belongs to the class of 1,3-dipolar cycloadditions, distinguished by the selective and catalyst-free formation of isoxazoline adducts through the interaction of a nitrile oxide dipole with a dipolarophilic alkene or alkyne under physiological conditions.

837

Publications

28.4K

Citations

2.3K

Authors

605

Institutions

Publications per year

2017–2026

87

Parents

Publications

837

Copper(I)-Catalyzed Synthesis of Azoles. DFT Study Predicts Unprecedented Reactivity and Intermediates

Fahmi Himo, Timothy Lovell, Robert Hilgraf et al. · Journal of the American Chemical Society · 2004 · 1.7K citations

, , +16

Stereoselective nitrile oxide cycloadditions to chiral allyl ethers and alcohols. The inside alkoxy effect

K. N. Houk, S.R. Moses, Yun Wu et al. · Journal of the American Chemical Society · 1984 · 274 citations

, , +9

One-Pot Copper(I)-Catalyzed Synthesis of 3,5-Disubstituted Isoxazoles

Trond Vidar Hansen, Peng Wu, Valery V. Fokin · The Journal of Organic Chemistry · 2005 · 244 citations

, , +12

Oxidation of Oximes to Nitrile Oxides with Hypervalent Iodine Reagents

Brian A. Mendelsohn, Shelley Lee, Simon Kim et al. · Organic Letters · 2009 · 214 citations

, , +3

Metal-Assisted Stereocontrol of 1,3-Dipolar Cycloaddition Reactions

Shuji Kanemasa · Synlett · 2002 · 206 citations

, , +12

1–5 of 837

Authors

2.3K

  1. SK
    Shuji Kanemasa

    Kyushu University, Japan

    22 publications · 1K citations

    18

    h-index

  2. PC
    Pierluigi Caramella

    University of Pavia, Italy

    15 publications · 518 citations

    14

    h-index

  3. KN
    K. N. Houk

    University of California, Los Angeles, United States

    14 publications · 968 citations

    14

    h-index

  4. MJ
    Mark J. Kurth

    University of California, Davis, United States

    14 publications · 326 citations

    13

    h-index

  5. EM
    Erick M. Carreira

    ETH Zurich, Switzerland

    13 publications · 766 citations

    12

    h-index

1–5 of 2.3K

Institutions

605

  1. Kyushu University

    Fukuoka, Japan

    17 h-index

    62 publications

    1.8K citations

  2. University of Pittsburgh

    Pittsburgh, United States

    17 h-index

    38 publications

    1.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    48 publications

    1.3K citations

  4. University of Milan

    Milan, Italy

    13 h-index

    54 publications

    1.2K citations

  5. ETH Zurich

    Zurich, Switzerland

    13 h-index

    39 publications

    2.5K citations

  6. The University of Tokyo

    Tokyo, Japan

    12 h-index

    34 publications

    922 citations

  7. University of Pavia

    Pavia, Italy

    12 h-index

    42 publications

    1.5K citations

  8. University of California, Davis

    Davis, United States

    12 h-index

    59 publications

    1.3K citations

1–8 of 605

Venues

  1. The Journal of Organic Chemistry

    JOC · 90 publications · 4K citations

    37

    h-index

  2. Tetrahedron Letters

    96 publications · 2.6K citations

    30

    h-index

  3. Organic Letters

    OL · 44 publications · 2.3K citations

    29

    h-index

  4. Tetrahedron

    69 publications · 1.9K citations

    28

    h-index

  5. Journal of the American Chemical Society

    JACS · 21 publications · 3.7K citations

    20

    h-index

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