Metabotropic glutamate receptor 1 blockade impairs acquisition and retention in a spatial Water maze task

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

François Conquet, Zafar I. Bashir, Ceri H. Davies et al. · Nature · 1994 · 743 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

F. Gasparini, Kurt Lingenhöhl, Natacha Stoehr et al. · Neuropharmacology · 1999 · 720 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice

Atsu Aiba · Cell · 1994 · 609 citations

Life Sciences, Neurobiology, Neuroscience +17

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity

Shigeyuki Chaki, Ryoko Yoshikawa, Shiho Hirota et al. · Neuropharmacology · 2003 · 251 citations

Medicine, Neuroscience, Pharmacology +12

The Behavioral Profile of the Potent and Selective mGlu5 Receptor Antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in Rodent Models of Anxiety

Chris S Busse, Jesse Brodkin, David Tattersall et al. · Neuropsychopharmacology · 2004 · 157 citations · Full text

Medicine, Neuroscience, Pharmacology +12