Concepedia

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

Alexei Degterev, Alexey A. Lugovskoy, Michael H. Cardone, Bradley Mulley, Gerhard Wagner, Timothy J. Mitchison, Junying Yuan

Nature Cell Biology · 2001 · 547 citations · 44 references

DOI

Concepts

References

44

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

Ruth M. Kluck, Ella Bossy‐Wetzel, Douglas R. Green et al. · Science · 1997 · 4.7K citations

, , +17

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text

, , +15

Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL

Jiping Zha, Hisashi Harada, Elizabeth Yang et al. · Cell · 1996 · 2.6K citations · Full text

, , +15

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

Steven W. Muchmore, Michael Sattler, Heng Liang et al. · Nature · 1996 · 1.5K citations

, , +11

Structure of Bcl-x <sub>L</sub> -Bak Peptide Complex: Recognition Between Regulators of Apoptosis

Michael Sattler, Heng Liang, David G. Nettesheim et al. · Science · 1997 · 1.5K citations

, , +17