Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer - Concepedia

Concepedia

Publication | Open Access

Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer

DOI Full Paper Access

135

Citations

30

References

2013

Year

Israel Cañadas, Federico Rojo, Álvaro Taus, Oriol Arpí, Montserrat Arumí-Uría, Lara Pijuán, Sílvia Menéndez, Sandra Zazo, Manuel Dómine, Marta Salido,

Clinical Cancer Research

Abstract

These results provide novel evidence on an important role of Met-dependent EMT in the adverse clinical behavior of SCLC and support clinical trials of Met inhibitors and chemotherapy in this fatal disease.

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