Concepedia

Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer

Israel Cañadas, Federico Rojo, Álvaro Taus, Oriol Arpí, Montserrat Arumí-Uría, Lara Pijuán, Sílvia Menéndez, Sandra Zazo, Manuel Dómine, Marta Salido,

Clinical Cancer Research · 2013 · 135 citations · 30 references

DOIFull text

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Abstract

These results provide novel evidence on an important role of Met-dependent EMT in the adverse clinical behavior of SCLC and support clinical trials of Met inhibitors and chemotherapy in this fatal disease.

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30

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