Ryanodine Receptor Phosphorylation by Calcium/Calmodulin-Dependent Protein Kinase II Promotes Life-Threatening Ventricular Arrhythmias in Mice With Heart Failure - Concepedia

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Ryanodine Receptor Phosphorylation by Calcium/Calmodulin-Dependent Protein Kinase II Promotes Life-Threatening Ventricular Arrhythmias in Mice With Heart Failure

DOI Full Paper Access

300

Citations

34

References

2010

Year

Ralph J. van Oort, Mark McCauley, Sayali S. Dixit, Laëtitia Pereira, Yi Yang, Jonathan L. Respress, Qiongling Wang, Angela C. De Almeida, Darlene G. Skapura, Mark E. Anderson,

Abstract

our results suggest that Ca(2+)/calmodulin-dependent protein kinase II phosphorylation of RyR2 Ca(2+) release channels at S2814 plays an important role in arrhythmogenesis and sudden cardiac death in mice with heart failure.

References

	Year	Citations

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