Concepedia

Publication | Closed Access

Liver-Specific Deletion of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Causes Hepatic Steatosis and Death

DOI

52

Citations

24

References

2012

Year

Shuichi Nagashima, Hiroaki Yagyu, Ken Ohashi, Fumiko Tazoe, Manabu Takahashi, Taichi Ohshiro, Bayasgalan Tumenbayar, Kenta Okada, Motohiro Sekiya, Jun-ichi Osuga,
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Hepatocyte HMGCR is essential for the survival of mice, and its abrogation elicits hepatic steatosis with jaundice and hypoglycemia.

References

YearCitations

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