A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity

Gefitinib-Sensitizing <i>EGFR</i> Mutations in Lung Cancer Activate Anti-Apoptotic Pathways

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Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

Shiqing Li, Karl R. Schmitz, Philip D. Jeffrey et al. · Cancer Cell · 2005 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Immunology +7

Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1

Gil Levkowitz, Hadassa Waterman, Seth A. Ettenberg et al. · Molecular Cell · 1999 · 992 citations

Systems Biology, Signal Transduction, Signaling Pathway +10

Clathrin-independent endocytosis of ubiquitinated cargos

Sara Sigismund, Tanja Woelk, Claudia Puri et al. · Proceedings of the National Academy of Sciences · 2005 · 830 citations · Full text

Cellular Physiology, Endocytic Pathway, Cell Signaling +16

Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function

Renato V. Iozzo, Alan D. Murdoch · The FASEB Journal · 1996 · 639 citations

Extracellular Environment, Glycobiology, Molecular Biology +17