Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

F. Michael Yakes, Bennett Van Houten · Proceedings of the National Academy of Sciences · 1997 · 1.8K citations

Life Sciences, Cell Biology, Molecular Biology +15

Sequence and gene organization of mouse mitochondrial DNA

Maureen J. Bibb, Richard A. Van Etten, C T Wright et al. · Cell · 1981 · 1.7K citations

Medicine, Genetics, Molecular Genetics +14

Coupled Leading- and Lagging-Strand Synthesis of Mammalian Mitochondrial DNA

Ian Holt, Heather E. Lorimer, Howard T. Jacobs · Cell · 2000 · 414 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Mitochondrial Adaptations to Obesity-Related Oxidant Stress

Shiqi Yang, Hong Zhu, Yunbo Li et al. · Archives of Biochemistry and Biophysics · 2000 · 367 citations

Life Sciences, Biology, Physiology +14

Acute Ethanol Administration Oxidatively Damages and Depletes Mitochondrial DNA in Mouse Liver, Brain, Heart, and Skeletal Muscles: Protective Effects of Antioxidants

Abdellah Mansouri, Christine Demeilliers, S Amsellem et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 229 citations

Pharmacy, Pharmacology, Toxicology +17