Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development

Somatic mutations affect key pathways in lung adenocarcinoma

Li Ding, Gad Getz, David A. Wheeler et al. · Nature · 2008 · 2.7K citations · Full text

Medicine, Genetics, Oncology +16

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

Leisa Johnson, Kim L. Mercer, Doron C. Greenbaum et al. · Nature · 2001 · 1.2K citations

Medicine, Molecular Genetics, Oncology +14

Suppression of non-small cell lung tumor development by the <i>let-7</i> microRNA family

Madhu Kumar, Stefan J. Erkeland, Ryan E. Pester et al. · Proceedings of the National Academy of Sciences · 2008 · 840 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Growth rate of small lung cancers detected on mass CT screening.

Masatoshi Hasegawa, S Sone, S Takashima et al. · British Journal of Radiology · 2000 · 572 citations

Medicine, Oncology, Radiology +17

Frequency and Distinctive Spectrum of <i>KRAS</i> Mutations in Never Smokers with Lung Adenocarcinoma

Gregory J. Riely, Mark G. Kris, Daniel G. Rosenbaum et al. · Clinical Cancer Research · 2008 · 569 citations · Full text

Medicine, Genetics, Oncology +15