On‐Demand Drug Release System for In Vivo Cancer Treatment through Self‐Assembled Magnetic Nanoparticles

Jae‐Hyun Lee, Kuan‐Ju Chen, Seung‐Hyun Noh, Mitch A. Garcia, Hao Wang, Wei‐Yu Lin, Heeyeong Jeong, Brian Junoh Kong, David B. Stout, Jinwoo Cheon,

Angewandte Chemie International Edition · 2013 · 230 citations · 37 references

Concepts

Abstract

On-demand drug release: Magnetothermally responsive drug-encapsulated supramolecular nanoparticles for on-demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.

References

37