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Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements
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2006
Year
Bioorganic ChemistryMolecular BiologyChemical Biology2,4-Diaminotriazine Nucleus PairProtein FoldingAntisense TherapyRecognition ElementsProteomicsMolecular Diversity2,4-Dioxotriazine NucleusBiochemistryOligodipeptoids TaggedOligonucleotideStructural BiologyNatural SciencesPeptide LibraryComputational BiologyOligodipeptoid BackbonesSystems BiologyMedicine
Pairing up: Oligodipeptide, oligodeoxydipeptide, or oligodipeptoid backbones tagged with the 2,4-diaminotriazine nucleus pair strongly with complementary DNA and RNA. This is in sharp contrast with the behavior of the 2,4-dioxotriazine nucleus, which does not act as a nucleobase in these systems. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z603207_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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