Abnormal lipid and apolipoprotein composition of major lipoprotein density classes in patients with chronic renal failure

Abstract

Results indicate that the characteristic feature of dyslipoproteinemia in CRF is the accumulation of partially delipidized TG-rich apoB-containing lipoproteins enriched in apoC-peptides and distributed characteristically in the IDL density-range irrespective of fasting TG concentrations. Increased levels of these ¿remnant lipoproteins' and reduced levels of HDL may represent risk factors for atherogenesis and progressive renal disease.