Effect of Pantothenic Acid on the Longevity of Mice

Abstract

1) Thirty-three young male and female C-57 black mice were given approximately 300 μg of calcium pantothenate daily in drinking water. Forty-one control mice did not receive the vitamin supplement. 2) The mean life span for the mice given supplementary calcium pantothenate was 653.1 days and that for the control mice was 549.8 days. The statistical difference between the 2 groups is P = 0.05 (T test) 0.01 (U test). 3) The mice which received the vitamin supplement maintained slightly greater body weight after they were approximately 250 days old.