Concepedia

MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia

Diana Schotte, R. X. De Menezes, Farhad Akbari Moqadam, Leila mohammadi Khankahdani, Ellen Lange-Turenhout, Christopher S. Chen, Rob Pieters, Monique L. den Boer

Haematologica · 2011 · 199 citations · 44 references

DOIFull text

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Abstract

Genetic subtypes and drug-resistant leukemic cells display characteristic microRNA signatures in pediatric acute lymphoblastic leukemia. Functional studies of discriminative and prognostically important microRNA may provide new insights into the biology of pediatric acute lymphoblastic leukemia.

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