An Orally Bioavailable Small Molecule Antagonist of CRTH2, Ramatroban (BAY u3405), Inhibits Prostaglandin D2-Induced Eosinophil Migration in Vitro

Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2

Hiroyuki Hirai, Kazuya Tanaka, Osamu Yoshie et al. · The Journal of Experimental Medicine · 2001 · 1.1K citations · Full text

Life Sciences, Immunology, Pharmacology +16

Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.

Robert A. Lewis, Nicholas A. Soter, P T Diamond et al. · The Journal of Immunology · 1982 · 588 citations · Full text

Life Sciences, Cell Biology, Immunology +15

Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor

Guillaume Monneret, Sylvie Gravel, Michael P. Diamond et al. · Blood · 2001 · 329 citations

Life Sciences, Immunology, Pharmacology +13

CRTH2, an orphan receptor of T‐helper‐2‐cells, is expressed on basophils and eosinophils and responds to mast cell‐derived factor(s)

Kinya Nagata, Hiroyuki Hirai, Kazuya Tanaka et al. · FEBS Letters · 1999 · 294 citations · Full text

Life Sciences, Cell Biology, Immunology +14

Eotaxin Induces a Rapid Release of Eosinophils and Their Progenitors From the Bone Marrow

Roger Palframan, Paul Collins, Timothy J. Williams et al. · Blood · 1998 · 292 citations · Full text

Life Sciences, Cell Biology, Immunology +10