Polymorphic Variants of SCN1A and EPHX1 Influence Plasma Carbamazepine Concentration, Metabolism and Pharmacoresistance in a Population of Kosovar Albanian Epileptic Patients - Concepedia

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Publication | Open Access

Polymorphic Variants of SCN1A and EPHX1 Influence Plasma Carbamazepine Concentration, Metabolism and Pharmacoresistance in a Population of Kosovar Albanian Epileptic Patients

DOI Full Paper Access

49

Citations

61

References

2015

Year

Armond Daci, Giangiacomo Beretta, Driton Vllasaliu, Aida Shala, Valbona Govori, Giuseppe Danilo Norata, Shaip Krasniqi

Abstract

The SCN1A IVS5-91G>A SNP is associated with susceptibility to epilepsy. SNPs in EPHX1 gene are influencing CBZ metabolism and disposition. CBZ plasma levels are not an indicator of resistance to the therapy.

References

	Year	Citations

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